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Classification of microbial immunomodulators

Classification of microbial immunomodulators under Kozlov I.G. (Head of Laboratory of Experimental Immunology and Immunopharmacology of the Federal Scientific and Clinical Center for Pediatric Hematology, Oncology and Immunology, Vice President of the Russian Scientific Society of Immunologists) 2005.

0 generation — Living bacteria

  • BCG
  • I generation — Lysates of microorganisms
  • Poly-pathogenic
  • Mono-pathogenic

II generation — Partially refined components

  • Lipopolysaccharides
  • Peptidoglycan
  • Ribosome
  • Nucleic acids

III generation — Minimal biologically active fragments

  • Glucosaminylmuramyldipeptide (GMDP) — (Licopid)
  • CpG oligonucleotides